EFNB2

Across TCGA patient cohorts, EFNB2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,437 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EFNB2-associated genes across cancer lineages are ARGLU1, SLAMF7, and IL2RB. Each is linked with EFNB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EFNB2-to-partner and partner-to-EFNB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNB2 versus ARGLU1 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNB2→partner) and Y-score (partner→EFNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARGLU1 →	+0.780	+0.751	<.001	.001	3	5
UCEC	SLAMF7 →	-0.994	-0.524	.004	.008	3	5
UCEC	IL2RB →	-0.721	-0.554	.002	.006	3	4
GBM	ZFYVE21 →	+0.535	+0.513	.001	<.001	3	4
HNSC	PIM2 →	-1.051	-0.465	<.001	<.001	3	4
BRCA	ACVR2A →	+0.532	+0.745	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,437 associations by consensus.

EFNB2 vs ARGLU1 — BRCA

Explore this scatter interactively →