EFNB1

Across TCGA pan-cancer cohorts, EFNB1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated EFNB1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher EFNB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EFNB1 expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

COAD, PDAC, and GBM are the cancer types where EFNB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.883	.016	54	view →
PDAC	OS	Median	IV	0.491	0.836	.024	4	view →
GBM	OS	Quartile	All	0.518	0.903	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

EFNB1–COAD (DFS)

Open the COAD breakdown →