EFNB1

Across TCGA cell cohorts, EFNB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,046 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EFNB1-associated GO terms across cancer lineages are Positive regulation of protein localization to nucleus, Cell-substrate junction organization, and Positive regulation of protein localization to cell periphery. Each is linked with EFNB1 in more than 10 cancer types. Because this analysis shows association rather than direction, both EFNB1-to-partner and partner-to-EFNB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to nucleus grouped by EFNB1-low versus EFNB1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNB1→partner) and Y-score (partner→EFNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of protein localization to nucleus →	+0.064	+0.989	.002	.002	2	11
URINARY_TRACT	Cell-substrate junction organization →	+0.171	+2.099	.001	<.001	3	10
LARGE_INTESTINE	Positive regulation of protein localization to cell periphery →	+0.083	+1.229	<.001	<.001	3	9
STOMACH	Ephrin receptor signaling pathway →	+0.144	+1.459	<.001	.004	3	9
SKIN	Regulation of protein localization to nucleus →	+0.061	+1.282	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Transepithelial water transport →	+2.287	+2.400	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,046 associations by consensus.

Positive regulation of protein localization to nucleus by EFNB1 expression — SOFT_TISSUE

Explore this box plot interactively →