Across TCGA patient cohorts, EFNA5 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFNA5-associated genes across cancer lineages are Epithelial cells, CLP, and Endothelial cells. Each is linked with EFNA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFNA5-to-partner and partner-to-EFNA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA5→partner) and Y-score (partner→EFNA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.069	-1.692	.016	.043	3	2
UCEC	CLP →	-0.053	-1.863	.036	.017	3	1
UCEC	Endothelial cells →	-0.032	-2.107	.038	.018	3	1
UCEC	lymphatic Endothelial cells →	-0.019	-1.660	.042	.044	3	1
UCEC	Basophils →	+0.137	+1.906	.044	.017	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

EFNA5 survival (RNA) · tumor vs normal (RNA) · all EFNA5 data types