EFNA4

Across TCGA patient cohorts, EFNA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,950 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFNA4-associated proteins across cancer lineages are GIMAP8, HSPA14, and PSME2. Each is linked with EFNA4 in more than 5 cancer types. Because this analysis shows association rather than direction, both EFNA4-to-partner and partner-to-EFNA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNA4 versus GIMAP8 in HNSC, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA4→partner) and Y-score (partner→EFNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GIMAP8 →	-0.489	-0.728	<.001	.001	3	6
BRCA	HSPA14 →	+0.315	+0.818	.002	.002	3	6
OV	PSME2 →	-0.405	-0.535	<.001	<.001	3	5
PDAC	DCAF7 →	+0.363	+0.680	<.001	<.001	3	5
OV	GGPS1 →	+0.387	+0.503	.001	.002	3	5
LSCC	GIMAP7 →	-0.592	-0.703	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,950 associations by consensus.

EFNA4 vs GIMAP8 — HNSC

Explore this scatter interactively →