EFNA4

Across TCGA patient cohorts, EFNA4 protein abundance is significantly associated with the RNA expression of many other genes, with 483 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFNA4-associated genes across cancer lineages are SH3BP1, CEP128, and VRK1. Each is linked with EFNA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFNA4-to-partner and partner-to-EFNA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNA4 versus SH3BP1 in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA4→partner) and Y-score (partner→EFNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SH3BP1 →	-0.501	-0.631	.002	<.001	3	1
UCEC	CEP128 →	-0.747	-0.626	.001	.001	3	1
UCEC	VRK1 →	-0.597	-0.503	.003	.007	3	1
UCEC	PLTP →	-1.321	-0.663	.008	.003	3	1
UCEC	CDC25B →	-0.788	-0.569	.006	.002	3	1
UCEC	TRIB3 →	-1.644	-0.639	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 483 associations by consensus.

EFNA4 vs SH3BP1 — UCEC

Explore this scatter interactively →