EFNA3

Across TCGA patient cohorts, EFNA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,265 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFNA3-associated proteins across cancer lineages are SAMHD1, ARHGAP15, and ARHGAP15_S64. Each is linked with EFNA3 in more than 5 cancer types. Because this analysis shows association rather than direction, both EFNA3-to-partner and partner-to-EFNA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNA3 versus SAMHD1 in HNSC, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA3→partner) and Y-score (partner→EFNA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAMHD1 →	-0.551	-0.851	<.001	<.001	3	6
HNSC	ARHGAP15 →	-0.580	-0.828	<.001	<.001	3	5
LSCC	ARHGAP15_S64 →	-0.807	-0.746	<.001	<.001	3	5
HNSC	ARHGAP25_S488 →	-0.765	-1.002	<.001	<.001	3	5
LSCC	ARHGAP25_S512 →	-0.752	-1.022	<.001	<.001	3	5
CCRCC	PARP14 →	-0.332	-0.526	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,265 associations by consensus.

EFNA3 vs SAMHD1 — HNSC

Explore this scatter interactively →