EFNA2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EFNA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,691 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EFNA2-associated proteins across cancer lineages are SLFN5, PALM_S116, and PALM_S162. Each is linked with EFNA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFNA2-to-partner and partner-to-EFNA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNA2 versus SLFN5 in GBM, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA2→partner) and Y-score (partner→EFNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSLFN5 →-0.358-0.711<.001<.00134
HNSCPALM_S116 →+0.936+0.417<.001<.00134
LSCCPALM_S162 →+0.575+0.426<.001.00134
PDACC8orf82 →+0.355+0.739<.001<.00133
GBMCAST_S575 →-0.527-0.764<.001<.00133
GBMCCDC9B →-0.475-0.679.005.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,691 associations by consensus.

EFNA2 vs SLFN5 — GBM

Per-sample scatter of EFNA2 vs SLFN5 in GBM (Pearson r = -0.46).

Explore this scatter interactively →

Exploration