EFNA2

Across TCGA patient cohorts, EFNA2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. COAD shows the largest number of these associations.

The most reproducible EFNA2-associated genes across cancer lineages are KRTAP19-6, MEF2AP1, and MIR3689D2. Each is linked with EFNA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFNA2-to-partner and partner-to-EFNA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-6 grouped by EFNA2-low versus EFNA2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA2→partner) and Y-score (partner→EFNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KRTAP19-6 →	+0.143	+7.930	<.001	.008	3	1
LUAD	MEF2AP1 →	+0.059	+7.930	<.001	.008	3	1
LUAD	MIR3689D2 →	+0.460	+7.930	<.001	.008	3	1
SKCM	ATP2B2-IT1 →	+0.074	+7.816	<.001	.008	3	1
SKCM	RNA5SP200 →	+0.488	+7.816	<.001	.008	3	1
SKCM	RNU6-709P →	+0.483	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

KRTAP19-6 by EFNA2 expression — LUAD

Explore this box plot interactively →