EFNA1

Across TCGA patient cohorts, EFNA1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,592 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFNA1-associated genes across cancer lineages are RUBCNL, IL21R, and CXCL12. Each is linked with EFNA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EFNA1-to-partner and partner-to-EFNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNA1 versus RUBCNL in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA1→partner) and Y-score (partner→EFNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RUBCNL →	-0.533	-0.513	.004	<.001	3	4
HNSC	IL21R →	-0.933	-0.545	<.001	<.001	3	4
HNSC	CXCL12 →	-0.961	-0.381	.001	.001	3	4
HNSC	IL10RA →	-0.778	-0.369	.004	.001	3	4
HNSC	GNPAT →	+0.447	+0.330	.007	.001	3	4
HNSC	APH1A →	+0.590	+0.408	.006	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,592 associations by consensus.

EFNA1 vs RUBCNL — HNSC

Explore this scatter interactively →