EFHD1

Across TCGA patient cohorts, EFHD1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,301 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EFHD1-associated genes across cancer lineages are SYNE3, ADAMTSL2, and SNED1. Each is linked with EFHD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EFHD1-to-partner and partner-to-EFHD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFHD1 versus SYNE3 in HNSC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHD1→partner) and Y-score (partner→EFHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SYNE3 →	+0.819	+0.552	<.001	<.001	3	7
UCEC	ADAMTSL2 →	+1.653	+0.855	<.001	<.001	3	7
OV	SNED1 →	+0.826	+0.845	.001	<.001	3	6
UCEC	ESCO2 →	-0.689	-0.630	<.001	<.001	3	6
OV	SLIT3 →	+1.155	+0.667	<.001	<.001	3	6
UCEC	MYLK →	+1.002	+0.632	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,301 associations by consensus.

EFHD1 vs SYNE3 — HNSC

Explore this scatter interactively →