EFHD1

Across TCGA cell cohorts, EFHD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,729 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EFHD1-associated GO terms across cancer lineages are Chromosomal 5-methylcytosine DNA demethylation pathway, Positive regulation of stem cell population maintenance, and Pattern recognition receptor signaling pathway. Each is linked with EFHD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both EFHD1-to-partner and partner-to-EFHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal 5-methylcytosine DNA demethylation pathway grouped by EFHD1-low versus EFHD1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHD1→partner) and Y-score (partner→EFHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.173	+1.689	.001	.002	3	9
BONE	Positive regulation of stem cell population maintenance →	+0.049	+1.685	.008	.004	3	9
UPPER_AERODIGESTIVE_TRACT	Pattern recognition receptor signaling pathway →	-0.061	-1.366	<.001	.002	3	9
OESOPHAGUS	Golgi to plasma membrane transport →	+0.103	+1.454	<.001	.006	3	8
STOMACH	Regulation of monoatomic cation transmembrane transport →	-0.053	-1.719	<.001	.001	3	8
STOMACH	Regulation of DNA-templated transcription initiation →	+0.050	+2.124	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,729 associations by consensus.

Chromosomal 5-methylcytosine DNA demethylation pathway by EFHD1 expression — STOMACH

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