Across TCGA patient cohorts, EFHC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,470 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EFHC2-associated proteins across cancer lineages are IFT74, TPPP3, and IFT57. Each is linked with EFHC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EFHC2-to-partner and partner-to-EFHC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHC2→partner) and Y-score (partner→EFHC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IFT74 →	+0.392	+0.742	<.001	<.001	3	6
UCEC	TPPP3 →	+1.732	+1.528	<.001	<.001	3	5
UCEC	IFT57 →	+0.426	+1.255	<.001	<.001	3	5
UCEC	TRAF3IP1 →	+0.440	+1.444	<.001	<.001	3	5
UCEC	TTC25_S542 →	+1.357	+1.671	<.001	<.001	3	5
UCEC	PPIL6_S16 →	+1.297	+1.450	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,470 associations by consensus.

Exploration

EFHC2 survival (RNA) · tumor vs normal (RNA) · all EFHC2 data types