Across TCGA patient cohorts, EFHC2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,280 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFHC2-associated genes across cancer lineages are LRRIQ1, DRC1, and TPPP3. Each is linked with EFHC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFHC2-to-partner and partner-to-EFHC2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHC2→partner) and Y-score (partner→EFHC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRRIQ1 →	+2.019	+0.992	<.001	<.001	3	4
UCEC	DRC1 →	+2.830	+0.728	<.001	.003	3	4
UCEC	TPPP3 →	+2.283	+0.573	.001	.002	3	4
UCEC	DNAI3 →	+1.754	+0.623	<.001	<.001	3	4
UCEC	TEKT1 →	+2.622	+0.830	<.001	<.001	3	4
UCEC	TOGARAM2 →	+1.706	+0.804	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,280 associations by consensus.

Exploration

EFHC2 survival (RNA) · tumor vs normal (RNA) · all EFHC2 data types