Across TCGA cell cohorts, EFHC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,289 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EFHC2-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Cytoplasmic translation. Each is linked with EFHC2 in more than 10 cancer types. Because this analysis shows association rather than direction, both EFHC2-to-partner and partner-to-EFHC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHC2→partner) and Y-score (partner→EFHC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.097	+0.569	.004	.001	3	11
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.096	+0.539	.004	.003	3	11
LUNG_NSCLC_LUAD	Cytoplasmic translation →	+0.057	+0.530	<.001	.001	3	10
BREAST	Mitochondrial electron transport, NADH to ubiquinone →	+0.085	+0.462	.003	.004	3	10
BREAST	Purine nucleoside triphosphate biosynthetic process →	+0.076	+0.473	.006	.009	3	10
BREAST	Purine ribonucleoside triphosphate biosynthetic process →	+0.076	+0.473	.006	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,289 associations by consensus.

Exploration

EFHC2 survival (RNA) · tumor vs normal (RNA) · all EFHC2 data types