EFHC1

Across TCGA patient cohorts, EFHC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,864 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EFHC1-associated proteins across cancer lineages are WDR35, PSME2, and CETN2. Each is linked with EFHC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EFHC1-to-partner and partner-to-EFHC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFHC1 versus WDR35 in UCEC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHC1→partner) and Y-score (partner→EFHC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR35 →	+0.393	+0.749	<.001	<.001	3	7
HNSC	PSME2 →	-0.448	-0.508	<.001	.001	3	7
UCEC	CETN2 →	+0.343	+0.638	<.001	<.001	3	6
UCEC	DYNC2H1 →	+0.506	+0.609	<.001	<.001	3	6
BRCA	IFT122 →	+0.396	+0.948	<.001	<.001	3	6
BRCA	IFT140 →	+0.545	+0.904	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,864 associations by consensus.

EFHC1 vs WDR35 — UCEC

Explore this scatter interactively →