EFHC1

Across TCGA cell cohorts, EFHC1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,160 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFHC1-associated genes across cancer lineages are STK36, CEP126, and GLB1L. Each is linked with EFHC1 in more than 12 cancer types. Because this analysis shows association rather than direction, both EFHC1-to-partner and partner-to-EFHC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFHC1 versus STK36 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHC1→partner) and Y-score (partner→EFHC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	STK36 →	+1.804	+1.590	<.001	<.001	3	13
STOMACH	CEP126 →	+1.509	+1.886	<.001	<.001	3	12
BREAST	GLB1L →	+0.993	+1.336	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	CEP162 →	+0.939	+1.527	<.001	<.001	3	11
LUNG_SCLC	TTC25 →	+1.033	+1.315	<.001	<.001	3	11
LUNG_SCLC	WDR19 →	+1.390	+1.414	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,160 associations by consensus.

EFHC1 vs STK36 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →