EFEMP2

Across TCGA patient cohorts, EFEMP2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,185 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EFEMP2-associated genes across cancer lineages are MYL9, CLEC11A, and CCN2. Each is linked with EFEMP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both EFEMP2-to-partner and partner-to-EFEMP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFEMP2 versus MYL9 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFEMP2→partner) and Y-score (partner→EFEMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MYL9 →	+1.393	+0.571	<.001	.002	3	10
OV	CLEC11A →	+1.383	+0.692	<.001	<.001	3	10
OV	CCN2 →	+1.851	+0.786	<.001	<.001	3	10
OV	LTBP2 →	+1.239	+0.626	<.001	<.001	3	10
CCRCC	PTGIS →	+2.144	+1.111	<.001	<.001	3	10
OV	ISLR →	+1.539	+0.653	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,185 associations by consensus.

EFEMP2 vs MYL9 — OV

Explore this scatter interactively →