EFCC1

Across TCGA patient cohorts, EFCC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,896 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EFCC1-associated proteins across cancer lineages are DDAH1, EFCC1_S394, and AK1. Each is linked with EFCC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EFCC1-to-partner and partner-to-EFCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFCC1 versus DDAH1 in OV, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCC1→partner) and Y-score (partner→EFCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDAH1 →	+0.667	+1.096	<.001	<.001	3	7
BRCA	EFCC1_S394 →	+1.220	+1.685	<.001	<.001	3	7
CCRCC	AK1 →	+0.568	+0.771	<.001	<.001	3	7
CCRCC	TNS2_S120 →	+0.637	+0.924	<.001	<.001	3	7
OV	SPTAN1 →	+0.292	+0.823	<.001	<.001	3	7
UCEC	SPTBN1 →	+0.340	+0.818	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,896 associations by consensus.

EFCC1 vs DDAH1 — OV

Explore this scatter interactively →