EFCC1

Across TCGA patient cohorts, EFCC1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,023 significant associations in total. OV shows the largest number of these associations.

The most reproducible EFCC1-associated genes across cancer lineages are OR6F1, AGBL5-AS1, and RASD2. Each is linked with EFCC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCC1-to-partner and partner-to-EFCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFCC1 versus OR6F1 in BRCA, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCC1→partner) and Y-score (partner→EFCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR6F1 →	+0.197	+0.856	.003	.002	3	2
BRCA	AGBL5-AS1 →	+0.623	+0.856	.002	.002	3	2
LUAD	RASD2 →	+0.544	+0.595	<.001	.006	3	1
LUAD	LIPG →	+0.852	+0.597	<.001	.009	3	1
LUAD	COTL1 →	+0.707	+0.622	.004	.007	3	1
LUAD	FOXF1 →	+0.476	+0.435	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,023 associations by consensus.

EFCC1 vs OR6F1 — BRCA

Explore this scatter interactively →