EFCC1

Across TCGA cell cohorts, EFCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,479 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EFCC1-associated GO terms across cancer lineages are AMP catabolic process, Muscle organ development, and Regulation of calcium ion transport into cytosol. Each is linked with EFCC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EFCC1-to-partner and partner-to-EFCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMP catabolic process grouped by EFCC1-low versus EFCC1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCC1→partner) and Y-score (partner→EFCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	AMP catabolic process →	-1.381	-0.680	<.001	<.001	3	7
OVARY	Muscle organ development →	-0.038	-0.138	.002	.007	2	7
SOFT_TISSUE	Regulation of calcium ion transport into cytosol →	-0.212	-0.283	<.001	.003	3	6
OVARY	Negative regulation of transcription by RNA polymerase III →	+0.119	+0.172	<.001	.005	3	6
OVARY	Regulation of hemostasis →	-0.138	-0.193	<.001	.004	3	6
OVARY	Cytoplasmic translation →	+0.049	+0.148	.005	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,479 associations by consensus.

AMP catabolic process by EFCC1 expression — BREAST

Explore this box plot interactively →