Across TCGA patient cohorts, EFCAB6 mutation is significantly associated with the RNA expression of many other genes, with 6,659 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB6-associated genes across cancer lineages are AUNIP, SNU13, and ZWINT. Each is linked with EFCAB6 in more than 4 cancer types. Because this analysis shows association rather than direction, both EFCAB6-to-partner and partner-to-EFCAB6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB6→partner) and Y-score (partner→EFCAB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AUNIP →	+0.581	+1.725	<.001	<.001	3	5
UCEC	SNU13 →	+0.319	+1.811	<.001	<.001	3	4
UCEC	ZWINT →	+0.723	+1.874	<.001	<.001	3	4
UCEC	STIL →	+0.427	+1.332	<.001	<.001	3	4
COAD	EXOSC9 →	+0.439	+2.625	<.001	.005	3	4
UCEC	PSMC3IP →	+0.722	+2.212	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,659 associations by consensus.

Exploration

EFCAB6 survival (RNA) · tumor vs normal (RNA) · all EFCAB6 data types