Across TCGA patient cohorts, EFCAB6 mutation is significantly associated with the total protein of many other genes, with 75 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB6-associated genes across cancer lineages are ASNS, eIF4E, and NF-kB-p65_pS536. Each is linked with EFCAB6 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFCAB6-to-partner and partner-to-EFCAB6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB6→partner) and Y-score (partner→EFCAB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	ASNS →	+0.433	+3.000	.017	.034	3	4
COAD	eIF4E →	+0.208	+3.025	.001	<.001	2	4
COAD	NF-kB-p65_pS536 →	-0.433	-2.987	.028	.035	3	3
UCEC	ERK2 →	+0.151	+1.289	.003	.018	3	3
UCEC	PCNA →	+0.187	+1.387	.001	.001	3	3
UCEC	Annexin-1 →	+0.599	+2.523	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

Exploration

EFCAB6 survival (RNA) · tumor vs normal (RNA) · all EFCAB6 data types