Across TCGA cell cohorts, EFCAB6 mutation is significantly associated with the RNA expression of many other genes, with 298 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFCAB6-associated genes across cancer lineages are SCGB3A1, TACC1, and CNGA3. Each is linked with EFCAB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB6-to-partner and partner-to-EFCAB6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB6→partner) and Y-score (partner→EFCAB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SCGB3A1 →	+0.156	+3.459	.002	.002	3	2
BLOOD_Leukemia	TACC1 →	+1.015	+3.199	.001	.007	3	2
URINARY_TRACT	CNGA3 →	+0.016	+3.700	<.001	.002	3	1
KIDNEY	BSX →	+0.063	+5.000	<.001	.005	3	1
SKIN	RMI2 →	+0.728	+3.212	.002	.006	3	1
SKIN	C5orf52 →	+0.025	+3.192	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 298 associations by consensus.

Exploration

EFCAB6 survival (RNA) · tumor vs normal (RNA) · all EFCAB6 data types