Across TCGA cell cohorts, EFCAB6 mutation is significantly associated with the mutation status of many other genes, with 4,896 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFCAB6-associated genes across cancer lineages are RBM10, FRAS1, and SDK2. Each is linked with EFCAB6 in more than 4 cancer types. Because this analysis shows association rather than direction, both EFCAB6-to-partner and partner-to-EFCAB6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB6→partner) and Y-score (partner→EFCAB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RBM10 →	+3.662	+2.772	.002	.002	1	5
LARGE_INTESTINE	FRAS1 →	+1.807	+2.115	.001	.001	1	5
CNS	SDK2 →	+3.762	+3.584	.003	.003	1	5
BONE	PCDHA1 →	+4.437	+5.000	.007	.007	1	4
PANCREAS	ADCY9 →	+5.115	+5.115	.005	.005	1	4
BREAST	IPO8 →	+4.857	+4.297	.009	.009	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,896 associations by consensus.

Exploration

EFCAB6 survival (RNA) · tumor vs normal (RNA) · all EFCAB6 data types