EFCAB6-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, EFCAB6-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated EFCAB6-AS1 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher EFCAB6-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EFCAB6-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and UVM show a favorable association.

CESC, UVM, and THCA are the cancer types where EFCAB6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCOSQuartileAll0.9130.699<.001144view →
UVMOSTertileAll0.7990.383.00166view →
THCAOSMedianAll0.8041.000.00136view →
DLBCDFSQuartileAll0.3440.877.00133view →
BLCAOSMedianAll0.7680.665.00430view →
UCECDFSTertileAll0.7040.595.01628view →
PRADDFSMedianAll0.6960.885<.00118view →
READDFSTertileII,III,IV0.2460.612.01415view →
CHOLOSQuartileAll0.8920.184.00612view →
HNSCOSQuartileAll0.2970.477.00611view →
STADDFSQuartileIV0.1370.501.0149view →
KIRCDFSQuartileAll0.4920.681.0376view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration