EFCAB5

Across TCGA patient cohorts, EFCAB5 mutation is significantly associated with the RNA expression of many other genes, with 6,298 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB5-associated genes across cancer lineages are CENPM, UBE2T, and RNU6-178P. Each is linked with EFCAB5 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFCAB5-to-partner and partner-to-EFCAB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPM grouped by EFCAB5-low versus EFCAB5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB5→partner) and Y-score (partner→EFCAB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPM →	+0.633	+2.440	<.001	<.001	3	4
UCEC	UBE2T →	+0.655	+1.850	<.001	<.001	3	4
READ	RNU6-178P →	+0.578	+4.361	<.001	.006	3	3
READ	MIR4797 →	+0.819	+5.054	<.001	.001	3	3
LUSC	PABPC1P13 →	+0.019	+4.204	<.001	<.001	3	3
LUSC	SNORD65C →	+0.546	+2.082	.005	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,298 associations by consensus.

CENPM by EFCAB5 expression — UCEC

Explore this box plot interactively →