EFCAB5

Across TCGA cell cohorts, EFCAB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,624 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EFCAB5-associated GO terms across cancer lineages are Protein polymerization, Regulation of pattern recognition receptor signaling pathway, and Regulation of microtubule cytoskeleton organization. Each is linked with EFCAB5 in more than 6 cancer types. Because this analysis shows association rather than direction, both EFCAB5-to-partner and partner-to-EFCAB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polymerization grouped by EFCAB5-low versus EFCAB5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB5→partner) and Y-score (partner→EFCAB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein polymerization →	+0.060	+0.374	<.001	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of pattern recognition receptor signaling pathway →	+0.068	+0.307	<.001	.001	3	7
LUNG_SCLC	Regulation of microtubule cytoskeleton organization →	+0.076	+0.913	<.001	<.001	3	7
BREAST	Regulation of chromosome condensation →	+0.153	+0.452	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Protein autoubiquitination →	+0.039	+0.260	<.001	<.001	3	6
BLOOD_Leukemia	Positive regulation of mitotic cytokinesis →	+0.116	+0.634	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,624 associations by consensus.

Protein polymerization by EFCAB5 expression — SOFT_TISSUE

Explore this box plot interactively →