EFCAB3

Across TCGA patient cohorts, EFCAB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,723 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EFCAB3-associated GO terms across cancer lineages are Telomere maintenance, Response to UV, and Negative regulation of mitotic cell cycle. Each is linked with EFCAB3 in more than 14 cancer types. Because this analysis shows association rather than direction, both EFCAB3-to-partner and partner-to-EFCAB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance grouped by EFCAB3-low versus EFCAB3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB3→partner) and Y-score (partner→EFCAB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance →	+0.063	+0.158	<.001	<.001	3	14
STAD	Response to UV →	+0.063	+0.160	<.001	<.001	3	13
ESCA	Negative regulation of mitotic cell cycle →	+0.070	+0.150	<.001	.008	1	15
STAD	Regulation of centrosome cycle →	+0.063	+0.135	<.001	<.001	3	13
ESCA	Regulation of DNA replication →	+0.083	+0.140	<.001	.006	2	14
STAD	Regulation of DNA repair →	+0.062	+0.157	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,723 associations by consensus.

Telomere maintenance by EFCAB3 expression — STAD

Explore this box plot interactively →