EFCAB3

Across TCGA cell cohorts, EFCAB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 514 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EFCAB3-associated GO terms across cancer lineages are Oocyte growth, Response to hypobaric hypoxia, and Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with EFCAB3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFCAB3-to-partner and partner-to-EFCAB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by EFCAB3-low versus EFCAB3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB3→partner) and Y-score (partner→EFCAB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Oocyte growth →	+0.126	+0.013	.004	.006	3	3
LIVER	Response to hypobaric hypoxia →	+0.100	+0.020	<.001	.005	3	3
OVARY	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.068	+0.014	.005	.008	3	3
BREAST	Regulation of extrinsic apoptotic signaling pathway →	-0.051	-0.009	.007	.001	3	3
BLOOD_Lymphoma	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.066	+0.010	.002	.005	3	3
BLOOD_Lymphoma	Maturation of LSU-rRNA →	+0.066	+0.013	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

Oocyte growth by EFCAB3 expression — SKIN

Explore this box plot interactively →