Across TCGA patient cohorts, EFCAB2 protein abundance is significantly associated with the RNA expression of many other genes, with 950 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFCAB2-associated genes across cancer lineages are RPGR, ORAOV1P1, and SLC5A4. Each is linked with EFCAB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB2-to-partner and partner-to-EFCAB2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB2→partner) and Y-score (partner→EFCAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPGR →	+0.725	+0.607	.003	.006	3	2
LUAD	ORAOV1P1 →	+1.595	+0.528	<.001	.002	3	2
LUAD	SLC5A4 →	+1.018	+0.536	<.001	<.001	3	1
LUAD	PDGFB →	-0.850	-0.626	.001	.001	3	1
LUAD	NFKBIA →	+1.255	+0.704	.005	.001	3	1
LUAD	NFATC4 →	+0.787	+0.441	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 950 associations by consensus.

Exploration

EFCAB2 survival (RNA) · tumor vs normal (RNA) · all EFCAB2 data types