Across TCGA patient cohorts, EFCAB2 mutation is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB2-associated genes across cancer lineages are HSBP1P2, SNORD114-11, and RNA5SP297. Each is linked with EFCAB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB2-to-partner and partner-to-EFCAB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB2→partner) and Y-score (partner→EFCAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSBP1P2 →	+0.666	+3.541	.004	.007	3	2
UCEC	SNORD114-11 →	+0.428	+4.292	<.001	.006	3	2
UCEC	RNA5SP297 →	+0.595	+3.297	.001	.002	3	2
UCEC	NUTF2P8 →	+0.257	+3.982	<.001	<.001	3	1
UCEC	YPEL5P2 →	+0.534	+3.763	<.001	.002	3	1
UCEC	ZYXP1 →	+0.270	+4.292	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

Exploration

EFCAB2 survival (RNA) · tumor vs normal (RNA) · all EFCAB2 data types