Across TCGA cell cohorts, EFCAB2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFCAB2-associated genes across cancer lineages are GSG1L2, CBLN4, and HBG1. Each is linked with EFCAB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB2-to-partner and partner-to-EFCAB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB2→partner) and Y-score (partner→EFCAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1
BLOOD_Leukemia	CBLN4 →	+0.006	+5.539	<.001	.003	3	1
SKIN	HBG1 →	+0.124	+3.793	<.001	.007	3	1
LARGE_INTESTINE	GPR15 →	+1.489	+3.443	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

EFCAB2 survival (RNA) · tumor vs normal (RNA) · all EFCAB2 data types