EFCAB14

Across TCGA patient cohorts, EFCAB14 protein abundance is significantly associated with the RNA expression of many other genes, with 6,546 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EFCAB14-associated genes across cancer lineages are FMNL1, TRAJ23, and TRAJ11. Each is linked with EFCAB14 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFCAB14-to-partner and partner-to-EFCAB14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFCAB14 versus FMNL1 in HNSC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB14→partner) and Y-score (partner→EFCAB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FMNL1 →	-0.482	-0.240	.001	.001	3	4
HNSC	TRAJ23 →	-1.381	-0.221	<.001	<.001	3	3
HNSC	TRAJ11 →	-1.485	-0.277	<.001	<.001	3	3
HNSC	TRAJ10 →	-1.343	-0.221	<.001	<.001	3	3
HNSC	KRT8P34 →	-0.388	-0.213	.001	.001	3	3
HNSC	TRAJ37 →	-1.405	-0.288	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,546 associations by consensus.

EFCAB14 vs FMNL1 — HNSC

Explore this scatter interactively →