EFCAB12

Across TCGA cell cohorts, EFCAB12 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EFCAB12-associated genes across cancer lineages are DKK4, C9, and TPO. Each is linked with EFCAB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB12-to-partner and partner-to-EFCAB12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DKK4 grouped by EFCAB12-low versus EFCAB12-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB12→partner) and Y-score (partner→EFCAB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DKK4 →	+0.180	+2.886	<.001	.006	3	1
BLOOD_Leukemia	C9 →	+0.912	+3.038	<.001	.004	3	1
BLOOD_Leukemia	TPO →	+0.806	+3.853	<.001	.002	3	1
BLOOD_Leukemia	RAI2 →	+0.068	+3.428	.005	.004	3	1
BLOOD_Leukemia	TRAT1 →	+1.890	+3.754	.009	.002	3	1
BLOOD_Leukemia	SPATA19 →	+0.011	+3.984	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

DKK4 by EFCAB12 expression — BLOOD_Leukemia

Explore this box plot interactively →