EFCAB1

Across TCGA pan-cancer cohorts, EFCAB1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated EFCAB1 data layer compared with 26 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher EFCAB1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated EFCAB1 expression acts as an unfavorable survival marker.

COAD, LUAD, and STAD are the cancer types where EFCAB1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.189	0.797	<.001	44	view →
LUAD	DFS	Median	All	0.207	0.667	<.001	27	view →
STAD	OS	Median	All	0.176	0.735	<.001	18	view →
LGG	OS	Median	All	0.103	0.896	<.001	12	view →
LIHC	OS	Median	All	0.098	0.777	<.001	12	view →
BLCA	OS	Median	All	0.188	0.687	.020	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

EFCAB1–COAD (DFS)

Open the COAD breakdown →