EEF2K

Across TCGA patient cohorts, EEF2K mutation is significantly associated with the RNA expression of many other genes, with 1,695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF2K-associated genes across cancer lineages are OR8B9P, ABHD5, and ARL1. Each is linked with EEF2K in more than 2 cancer types. Because this analysis shows association rather than direction, both EEF2K-to-partner and partner-to-EEF2K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B9P grouped by EEF2K-low versus EEF2K-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF2K→partner) and Y-score (partner→EEF2K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OR8B9P →	+0.074	+4.376	<.001	.002	3	3
UCEC	ABHD5 →	+0.626	+1.857	<.001	<.001	3	3
UCEC	ARL1 →	+0.356	+1.808	.002	.007	3	3
UCEC	NKD2 →	-1.143	-3.087	<.001	<.001	3	3
BLCA	MIR4285 →	+0.537	+2.928	<.001	.005	3	3
COAD	MIR5583-1 →	+0.548	+4.109	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,695 associations by consensus.

OR8B9P by EEF2K expression — LUAD

Explore this box plot interactively →