EEF2K

Across TCGA cell cohorts, EEF2K RNA expression is significantly associated with the go_rna of many other GO terms, with 3,875 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EEF2K-associated GO terms across cancer lineages are Positive regulation of intracellular estrogen receptor signaling pathway, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Positive regulation of T-helper 17 cell lineage commitment. Each is linked with EEF2K in more than 12 cancer types. Because this analysis shows association rather than direction, both EEF2K-to-partner and partner-to-EEF2K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular estrogen receptor signaling pathway grouped by EEF2K-low versus EEF2K-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF2K→partner) and Y-score (partner→EEF2K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.176	+1.076	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.121	+0.655	<.001	<.001	3	12
OVARY	Positive regulation of T-helper 17 cell lineage commitment →	+0.200	+0.684	<.001	.001	3	12
LARGE_INTESTINE	Metanephric proximal tubule development →	+0.250	+0.997	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.080	+0.735	.002	<.001	3	12
SOFT_TISSUE	Regulation of chromatin organization →	+0.079	+0.714	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,875 associations by consensus.

Positive regulation of intracellular estrogen receptor signaling pathway by EEF2K expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →