EEF2K

Across TCGA cell cohorts, EEF2K mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EEF2K-associated genes across cancer lineages are GLB1L3, KSR2, and SIX3. Each is linked with EEF2K in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF2K-to-partner and partner-to-EEF2K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GLB1L3 grouped by EEF2K-low versus EEF2K-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF2K→partner) and Y-score (partner→EEF2K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GLB1L3 →	+0.731	+2.716	<.001	.009	3	2
BLOOD_Leukemia	KSR2 →	+0.260	+3.798	.009	.004	3	2
LARGE_INTESTINE	SIX3 →	+0.643	+3.584	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
BREAST	VCY1B →	+1.297	+4.836	<.001	<.001	3	1
BREAST	VCY →	+0.739	+3.672	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

GLB1L3 by EEF2K expression — LARGE_INTESTINE

Explore this box plot interactively →