EEF2

Across TCGA pan-cancer cohorts, EEF2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated EEF2 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher EEF2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated EEF2 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where EEF2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.688	0.940	<.001	59	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.303	.004	13	view →
PDAC	DFS	Tertile	III,IV	0.420	0.986	.001	13	view →
LUAD	DFS	Tertile	All	0.996	0.867	.020	6	view →
OV	DFS	Median	All	0.861	1.000	.030	4	view →
GBM	DFS	Median	All	0.267	0.460	.004	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

EEF2–CCRCC (OS)

Open the CCRCC breakdown →