EEF2

Across TCGA cell cohorts, EEF2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EEF2-associated genes across cancer lineages are OXT, PABPC1L2B, and PLEKHS1. Each is linked with EEF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF2-to-partner and partner-to-EEF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OXT grouped by EEF2-low versus EEF2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF2→partner) and Y-score (partner→EEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OXT →	+0.057	+4.523	<.001	.004	3	1
UPPER_AERODIGESTIVE_TRACT	PABPC1L2B →	+0.099	+4.736	.009	.009	3	1
BLOOD_Leukemia	PLEKHS1 →	+0.072	+3.551	<.001	.008	3	1
BLOOD_Leukemia	DEFB108B →	+0.106	+3.684	<.001	.004	3	1
BLOOD_Leukemia	OR10T2 →	+0.608	+3.691	<.001	.002	3	1
BLOOD_Leukemia	GUCA2A →	+0.026	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OXT by EEF2 expression — BLOOD_Lymphoma

Explore this box plot interactively →