EEF1G

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, EEF1G Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated EEF1G data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher EEF1G Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated EEF1G expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

SARC, PRAD, and UCEC are the cancer types where EEF1G Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SARCDFSMedianAll0.1090.611.0306view →
PRADDFSMedianAll0.0850.774<.0016view →
UCECDFSMedianAll1.0000.831.0382view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

EEF1G–SARC (DFS)

Kaplan–Meier survival curve for EEF1G mutant vs wild-type samples in SARC.

Open the SARC breakdown →

Exploration