EEF1G

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EEF1G mutation is significantly associated with the RNA expression of many other genes, with 429 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1G-associated genes across cancer lineages are LINC00850, SNORA36A, and MIR548A3. Each is linked with EEF1G in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1G-to-partner and partner-to-EEF1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00850 grouped by EEF1G-low versus EEF1G-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1G→partner) and Y-score (partner→EEF1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC00850 →+0.046+4.591<.001<.00132
SKCMSNORA36A →+0.250+3.145<.001.00432
SKCMMIR548A3 →+0.760+3.641.001.00532
LUSCRNU7-90P →+0.590+5.093<.001.00832
CESCRN7SKP263 →+0.166+6.569<.001.00132
UCECRNU6-927P →+0.194+2.434.004.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 429 associations by consensus.

LINC00850 by EEF1G expression — SKCM

Box plot of LINC00850 in EEF1G-low vs EEF1G-high samples in SKCM.

Explore this box plot interactively →

Exploration