EEF1G

Across TCGA patient cohorts, EEF1G mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1G-associated genes across cancer lineages are EGFR, MSH6, and p90 RSK. Each is linked with EEF1G in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1G-to-partner and partner-to-EEF1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR grouped by EEF1G-low versus EEF1G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1G→partner) and Y-score (partner→EEF1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.180	-3.169	.009	.019	3	1
UCEC	MSH6 →	-0.322	-2.999	.025	.035	3	1
UCEC	p90 RSK →	+0.180	+2.820	.031	.001	3	1
UCEC	Annexin-1 →	+0.677	+2.479	.003	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.752	+2.341	.003	.019	3	1
UCEC	Caspase-8 →	-0.255	-3.432	.020	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

EGFR by EEF1G expression — UCEC

Explore this box plot interactively →