EEF1G

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EEF1G mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EEF1G-associated genes across cancer lineages are TCF21, TACR3, and OR10T2. Each is linked with EEF1G in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1G-to-partner and partner-to-EEF1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCF21 grouped by EEF1G-low versus EEF1G-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1G→partner) and Y-score (partner→EEF1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaTCF21 →+0.011+4.705<.001.00331
BLOOD_LeukemiaTACR3 →+0.038+5.060<.001.00131
BLOOD_LeukemiaOR10T2 →+0.707+4.276<.001.00731
BLOOD_LeukemiaOR10R2 →+1.349+4.551.004.00431
SKINPNMA6E →+0.037+4.095<.001.00931
LARGE_INTESTINESSMEM1 →+0.029+4.029<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

TCF21 by EEF1G expression — BLOOD_Leukemia

Box plot of TCF21 in EEF1G-low vs EEF1G-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration