EEF1E1

Across TCGA pan-cancer cohorts, EEF1E1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated EEF1E1 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EEF1E1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EEF1E1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

HNSC, LUAD, and OV are the cancer types where EEF1E1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.836	0.517	<.001	64	view →
LUAD	OS	Median	All	0.598	0.839	.012	10	view →
OV	DFS	Median	All	0.914	0.565	.045	4	view →
CCRCC	OS	Median	IV	0.150	0.785	.040	4	view →
PDAC	OS	Median	All	0.779	0.945	.028	4	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.840	.041	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

EEF1E1–HNSC (DFS)

Open the HNSC breakdown →