EEF1E1

Across TCGA patient cohorts, EEF1E1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1E1-associated genes across cancer lineages are p62 Lck ligand, C-Raf, and FASN. Each is linked with EEF1E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1E1-to-partner and partner-to-EEF1E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by EEF1E1-low versus EEF1E1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1E1→partner) and Y-score (partner→EEF1E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.429	+2.817	.022	.036	3	1
UCEC	C-Raf →	+0.312	+3.000	<.001	.037	3	1
UCEC	FASN →	+0.553	+3.000	.015	.037	1	1
UCEC	NF2 →	+0.330	+3.000	.008	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

p62 Lck ligand by EEF1E1 expression — UCEC

Explore this box plot interactively →