EEF1DP3

Across TCGA patient cohorts, EEF1DP3 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1DP3-associated genes across cancer lineages are N-Cadherin, Smad3, and ATM. Each is linked with EEF1DP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both EEF1DP3-to-partner and partner-to-EEF1DP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-Cadherin grouped by EEF1DP3-low versus EEF1DP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1DP3→partner) and Y-score (partner→EEF1DP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	N-Cadherin →	+0.203	+2.999	.028	.035	3	3
UCEC	Smad3 →	+0.142	+2.321	.031	.034	3	2
UCEC	ATM →	-0.621	-3.156	.001	.018	3	2
UCEC	Caspase-8 →	-0.260	-2.807	.018	.003	3	2
UCEC	eIF4G →	+0.334	+3.321	.013	.009	3	1
UCEC	ERK2 →	+0.266	+2.807	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

N-Cadherin by EEF1DP3 expression — UCEC

Explore this box plot interactively →