EEF1D

Across TCGA patient cohorts, EEF1D mutation is significantly associated with the RNA expression of many other genes, with 1,276 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1D-associated genes across cancer lineages are GTF2IP22, RNA5SP414, and RNA5SP419. Each is linked with EEF1D in more than 2 cancer types. Because this analysis shows association rather than direction, both EEF1D-to-partner and partner-to-EEF1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GTF2IP22 grouped by EEF1D-low versus EEF1D-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1D→partner) and Y-score (partner→EEF1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GTF2IP22 →	+0.144	+6.599	<.001	<.001	3	3
BRCA	RNA5SP414 →	+0.216	+8.471	<.001	.005	3	2
BRCA	RNA5SP419 →	+0.898	+7.731	<.001	.009	3	2
UCEC	TMEM269 →	+0.169	+2.606	<.001	<.001	3	2
UCEC	RNA5SP411 →	+0.830	+1.853	<.001	.001	3	2
BLCA	RNA5SP502 →	+0.303	+5.411	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,276 associations by consensus.

GTF2IP22 by EEF1D expression — LUAD

Explore this box plot interactively →