EEF1D

Across TCGA patient cohorts, EEF1D mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEF1D-associated genes across cancer lineages are MSH6, eIF4E, and JNK2. Each is linked with EEF1D in more than 1 cancer types. Because this analysis shows association rather than direction, both EEF1D-to-partner and partner-to-EEF1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH6 grouped by EEF1D-low versus EEF1D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEF1D→partner) and Y-score (partner→EEF1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH6 →	-0.352	-2.105	.003	.017	3	2
UCEC	eIF4E →	+0.163	+1.807	.035	.025	3	1
UCEC	JNK2 →	+0.203	+2.348	.005	.018	3	1
UCEC	MEK1 →	+0.388	+2.000	.003	.009	3	1
UCEC	MSH2 →	-0.301	-1.848	<.001	.049	3	1
UCEC	Notch1 →	+0.117	+3.183	.023	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MSH6 by EEF1D expression — UCEC

Explore this box plot interactively →